Efficacy and Tolerability of Modified Atkins Diet in Japanese Children With Medication-Resistant Epilepsy

Seven Japanese patients aged 1.5–17 years with medication-resistant epilepsy were placed on the modified Atkins diet (MAD) for 3 weeks during admission to our hospital. Dietary carbohydrate was restricted to 10 g per day. Among the patients who could continue the diet for 3 weeks, 3 achieved the seizure reduction; 2 became seizure-free and 1 showed about 75% reduction in the seizure frequency within 10 days on the diet. The MAD was effective and well-tolerated in children with medication-resistant epilepsy in Japan.