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Use of the Modified Atkins Diet in Infantile Spasms Refractory to First-line Treatment

The modified Atkins diet was found to be effective and well tolerated in children with refractory infantile spasms Read More

A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal-weight Men

The results suggest that a short-term ketogenic diet does not have a deleterious effect on CVD risk profile and may improve the lipid disorders characteristic of atherogenic dyslipidemia. Read More

Very Low-carbohydrate and Low-fat Diets Affect Fasting Lipids and Postprandial Lipemia Differently in Overweight Men

The primary purpose of this study was to compare the effects of a very low-carbohydrate and a low-fat diet on fasting blood lipids and postprandial lipemia in overweight men. In a balanced, randomized, crossover design, overweight men consumed 2 experimental diets for 2 consecutive 6-wk periods. One was a very low-carbohydrate (<10% energy as carbohydrate) […] Read More

Weight Loss Leads to Reductions in Inflammatory Biomarkers After a Very Low-carbohydrate and Low-fat Diet in Overweight Men

The primary purpose of this study was to compare a very low-carbohydrate and a low-fat weight loss diet on inflammatory biomarkers in overweight men. Both the low-fat and the very low-carbohydrate diet resulted in significant decreases in absolute concentrations of hsTNF-alpha, hsIL-6, hs-CRP and sICAM-1. There was no significant change in absolute sP-selectin concentrations after […] Read More

A 6-Month, Office-Based, Low-Carbohydrate Diet Intervention in Obese Teens

The LCD appears to an effective and practical office-based intervention in obese teenagers. Read More

Meta-analysis of Prospective Cohort Studies Evaluating The Association of Saturated Fat With Cardiovascular Disease

A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD. More data are needed to elucidate whether CVD risks are likely to be influenced by the specific nutrients used to replace saturated fat. Read More

Saturated Fat, Carbohydrate, and Cardiovascular Disease

The substitution of dietary polyunsaturated fat for saturated fat has been shown to lower CVD risk, there are few epidemiologic or clinical trial data to support a benefit of replacing saturated fat with carbohydrate. Furthermore, particularly given the differential effects of dietary saturated fats and carbohydrates on concentrations of larger and smaller LDL particles, respectively, […] Read More

Efficacy and Tolerability of the Modified Atkins Diet in Adults With Pharmacoresistant Epilepsy: A Prospective Observational Study

The Modified Atkins Diet demonstrates modest efficacy as cotherapy for some adults with pharmacoresistant epilepsy and may be also helpful for weight loss. Financial and logistical barriers were significant factors for those who declined enrollment and for those who discontinued the study. Read More

Effects of a Low-carbohydrate Diet on Weight Loss and Cardiovascular Risk Factor in Overweight Adolescents

To compare the effects of a low-carbohydrate (LC) diet with those of a low-fat (LF) diet on weight loss and serum lipids in overweight adolescents. The LC group lost more weight (mean, 9.9 +/- 9.3 kg vs 4.1 +/- 4.9 kg) and had improvement in non-HDL cholesterol levels. There were no adverse effects on the […] Read More

The Effects of Low-Carbohydrate versus Conventional Weight Loss Diets in Severely Obese Adults: One-Year Follow-up of a Randomized Trial

Participants on a low-carbohydrate diet had more favorable overall outcomes at 1 year than did those on a conventional diet. Weight loss was similar between groups, but effects on atherogenic dyslipidemia and glycemic control were still more favorable with a low-carbohydrate diet after adjustment for differences in weight loss. Read More