Published: 09/16/2015

A Low-carbohydrate Diet in Overweight Patients Undergoing Stable Statin Therapy Raises High-density Lipoprotein and Lowers Triglycerides Substantially

This study was undertaken to evaluate the effect of a low-carbohydrate diet on the lipid levels in obese patients with known arteriosclerotic heart disease on chronic statin therapy. Triglyceride levels were lowered by 29.5%, HDL raised by 17.6%, and cholesterol decreased by 8.4%. The cholesterol/ HDL ratio changed from 5.31 to 3.78 and LDL cholesterol decreased by 5%. The addition of a low-carbohydrate diet for overweight patients with known coronary artery disease undergoing stable statin therapy causes significant weight loss and a favorable change in the lipid panel.


Friedman (2012). "Comparative Effects of Low-Carbohydrate High-Protein Versus Low-Fat Diets on the Kidney." Clin J Am Soc Nephrol 7.