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Saturated Fat, Carbohydrate, and Cardiovascular Disease

The substitution of dietary polyunsaturated fat for saturated fat has been shown to lower CVD risk, there are few epidemiologic or clinical trial data to support a benefit of replacing saturated fat with carbohydrate. Furthermore, particularly given the differential effects of dietary saturated fats and carbohydrates on concentrations of larger and smaller LDL particles, respectively, […] Read More

Efficacy and Tolerability of the Modified Atkins Diet in Adults With Pharmacoresistant Epilepsy: A Prospective Observational Study

The Modified Atkins Diet demonstrates modest efficacy as cotherapy for some adults with pharmacoresistant epilepsy and may be also helpful for weight loss. Financial and logistical barriers were significant factors for those who declined enrollment and for those who discontinued the study. Read More

Effects of a Low-carbohydrate Diet on Weight Loss and Cardiovascular Risk Factor in Overweight Adolescents

To compare the effects of a low-carbohydrate (LC) diet with those of a low-fat (LF) diet on weight loss and serum lipids in overweight adolescents. The LC group lost more weight (mean, 9.9 +/- 9.3 kg vs 4.1 +/- 4.9 kg) and had improvement in non-HDL cholesterol levels. There were no adverse effects on the […] Read More

The Effects of Low-Carbohydrate versus Conventional Weight Loss Diets in Severely Obese Adults: One-Year Follow-up of a Randomized Trial

Participants on a low-carbohydrate diet had more favorable overall outcomes at 1 year than did those on a conventional diet. Weight loss was similar between groups, but effects on atherogenic dyslipidemia and glycemic control were still more favorable with a low-carbohydrate diet after adjustment for differences in weight loss. Read More

Metabolic Effects of Weight Loss on a Very-Low-Carbohydrate Diet Compared With an Isocaloric High-Carbohydrate Diet in Abdominally Obese Subjects

Weight loss was similar in both groups (VLCHF & HCLF). Blood pressure, CRP, fasting glucose, and insulin reduced similarly with weight loss in both diets. The VLCHF diet produced greater decreases in triacylglycerols and increases in high-density lipoprotein cholesterol (HDL-C). Low-density lipoprotein cholesterol (LDL-C) remained unchanged in the VLCHF diet. Read More

Efficacy of the Atkins Diet as Therapy for Intractable Epilepsy in Children

Following three months of treatment with the Atkins diet, 16 patients (67%) had >50% decrease in seizure frequency, and 6 (25%) had >90% improvement, of whom 5 were seizure-free. Mean seizure frequency after the first, second and third months of treatment were significantly lower than at baseline. The Atkins diet can be considered as a […] Read More

Presence or absence of carbohydrates and the proportion of fat in a highprotein diet affect appetite suppression but not energy expenditure in normal weight human subjects fed in energy balance

Appetite suppression and fat oxidation were higher on a high-protein diet without than with carbohydrates exchanged for fat. Energy expenditure was not affected by the carbohydrate content of a high-protein diet. Read More

Diet-Induced Weight Loss Is Associated with Decreases in Plasma Serum Amyloid A and C-Reactive Protein Independent of Dietary Macronutrient Composition in Obese Subjects

The very low-carbohydrate dieters had a significantly greater decrease in LogSAA, but their weight loss also was significantly greater. In this study, the decreases in inflammatory markers correlated significantly with weight loss. Also, change in LogSAA correlated with change in insulin resistance. Thus, in otherwise healthy, obese women, weight loss was associated with significant decreases […] Read More

Ketogenic diet does not affect strength performance in elite artistic gymnasts

Data suggest that athletes who underwent a VLCKD with adequate protein intake lost weight and improved body composition without any negative changes in strength and power performance. Taken together these results suggest that a properly monitored and programmed ketogenic diet could be a useful, and safe, method to allow the athletes to reach their desired […] Read More

Nutrition and Acne: Therapeutic Potential of Ketogenic Diets

This review examines the evidence supporting an influence of various dietary components, such as ketogenic diet, on the development of acne particularly focusing on the role played by carbohydrates. Read More