The KD works quickly when effective, typically within the first 1–2 weeks. Starting the KD after a fasting periodmay lead to a more rapid, but equivalent long-term seizure reduction, confirming prior reports. If the KD has not led to seizure reduction after 2 months, it can probably be discontinued.
Month: September 2015
Ketogenic Diets: Evidence For Short- and Long-term Efficacy
This review discusses the animal and human evidence for both short- and long-term benefits of dietary therapies.
A Pilot Study of The Modified Atkins Diet For Sturge–Weber Syndrome
The modified Atkins diet (MAD) is a dietary treatment for epilepsy which does not restrict fluids or calories. This theoretically makes the MAD safer than the ketogenic diet for children with Sturge–Weber syndrome (SWS). Five children aged 4–18 years with SWS and at least monthly intractable seizures were started prospectively on the MAD for 6 months. All children had urinary ketosis and seizure improvement, including 3 with >50% seizure reduction.
Will Seizure Control Improve By Switching From The Modified Atkins Diet to The Traditional Ketogenic Diet?
A higher incidence of improvement with the KD occurred for those with myoclonic-astatic epilepsy including all who became seizure-free.
Prospective Study of the Modified Atkins Diet in Combination With a Ketogenic Liquid Supplement During the Initial Month
This study analyzed the combination of the Modified Atkins Diet and the supplement KetoCal in the treatment of intractible childhood epilepsy. The use of this ketogenic supplement increased daily fat intake and thus the ketogenic ratio but did not change urinary or serum ketosis. The addition of a ketogenic supplement to the modified Atkins diet during its initial month appears to be beneficial.
Dietary Therapies for Epilepsy
The two major nonpharmacologic treatments for patients with epilepsy are neurostimulation devices (e.g. vagus nerve stimulators) and dietary treatments (ketogenic). In this review, we will cover the latter treatments, namely, using diets.
Effects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance
Individuals on the very low carb diet had the highest resting metabolism.
Targeting insulin inhibition as a metabolic therapy in advanced cancer: A pilot safety and feasibility dietary trial in 10 patients
Insulin inhibition effected by dietary CHO restriction was found safe and feasible in 10 patients with advanced cancer.
Comparison of Low Fat and Low Carbohydrate Diets on Circulating Fatty Acid Composition and Markers of Inflammation
Overweight men and women with atherogenic dyslipidemia consumed ad libitum diets very low in carbohydrate (VLCKD) or low in fat (LFD) for 12 weeks. Both diets significantly decreased the concentration of several serum inflammatory markers, but there was an overall greater anti-inflammatory effect associated with the VLCKD. In summary, a very low carbohydrate diet resulted in profound alterations in fatty acid composition and reduced inflammation compared to a low fat diet.
A Randomized Trial of a Low-carbohydrate Diet For Obesity
The low-carbohydrate diet produced a greater weight loss (4%) than did the conventional diet for the first six months, but the differences were not significant at one year. The low-carbohydrate diet was associated with a greater improvement in some risk factors for coronary heart disease.