Comparison of Seizure Reduction and Serum Fatty Acid Levels After Receiving the Ketogenic and Modified Atkins Diet

Authors compared retrospectively the KD and modified Atkins diet in 27 children and also assessed serum long chain fatty acid profiles. We observed a preventive effect of both diets on the occurrence of status epilepticus. After 1 and 3 months of either diet, responders experienced a significant decrease in serum arachidonic acid concentration compared to non-responders. The KD and modified Atkins diet led to seizure reduction in this small pilot series, with slightly better results after 3 months with the KD, but not after 6 months.

Prospective Study of the Modified Atkins Diet in Combination With a Ketogenic Liquid Supplement During the Initial Month

This study analyzed the combination of the Modified Atkins Diet and the supplement KetoCal in the treatment of intractible childhood epilepsy. The use of this ketogenic supplement increased daily fat intake and thus the ketogenic ratio but did not change urinary or serum ketosis. The addition of a ketogenic supplement to the modified Atkins diet during its initial month appears to be beneficial.

Dietary Therapies for Epilepsy

The two major nonpharmacologic treatments for patients with epilepsy are neurostimulation devices (e.g. vagus nerve stimulators) and dietary treatments (ketogenic). In this review, we will cover the latter treatments, namely, using diets.