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The Human Metabolic Response to Chronic Ketosis Without Caloric Restriction: Physical and Biochemical Adaptation
These findings indicate that the ketotic state induced by the EKD was well tolerated in lean subjects; nitrogen balance was regained after brief adaptation, serum lipids were not pathologically elevated, and blood glucose oxidation at rest was measurably reduced while the subjects remained euglycemic. Read More
Comparison of Seizure Reduction and Serum Fatty Acid Levels After Receiving the Ketogenic and Modified Atkins Diet
Authors compared retrospectively the KD and modified Atkins diet in 27 children and also assessed serum long chain fatty acid profiles. We observed a preventive effect of both diets on the occurrence of status epilepticus. After 1 and 3 months of either diet, responders experienced a significant decrease in serum arachidonic acid concentration compared to […] Read More
Relative Intake of Macronutrients Impacts Risk of Mild Cognitive Impairment or Dementia
A dietary pattern with relatively high caloric intake from carbohydrates and low caloric intake from fat and proteins may increase the risk of MCI or dementia in elderly persons. Read More
Clinical Experience of a Diet Designed to Reduce Aging
A high-fat, adequate-protein, low-carbohydrate diet with nutritional supplementation led to improvements in serum factors related to the aging process. Read More
A Low-carbohydrate as Compared With a Low-fat Diet in Severe Obesity
Severely obese subjects with a high prevalence of diabetes or the metabolic syndrome lost more weight during six months on a carbohydrate-restricted diet than on a calorie- and fat-restricted diet, with a relative improvement in insulin sensitivity and triglyceride levels, even after adjustment for the amount of weight lost. Read More
Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors
LCD was shown to have favourable effects on body weight and major cardiovascular risk factors. Read More
Effects of a moderate low-carbohydrate diet on preferential abdominal fat loss and cardiovascular risk factors in patients with type 2 diabetes
Six months of a moderate LCD resulted in preferential VAT (visceral adipose tissue) loss only in women, with significant correlations between % change SAT (subcutaneous adipose tissue) and both change HDL and change FBG (fasting blood glucose), as well as between % change VAT and change TG. Authors results suggest that an LCD has the […] Read More
One Year Data From A Prospective Cohort of Low Carbohydrate Dieters
Most CCARBS participants reported they had: More stable moods on a low carb diet, Better appetite control than with a conventional weight loss diet, Preferred food choices on a lower carb diet compared to a conventional weight loss diet. One year weight changes in CCARBS participants were: 26.5% lost weight; 39.0% maintained their weight; 34.5% […] Read More
A Randomized Study Comparing the Effects of a Low-carbohydrate Diet and a Conventional Diet on Lipoprotein Subfractions and C-reactive Protein Levels in Patients With Severe Obesity
In this 6-month study involving severely obese subjects, we found an overall favorable effect of a low-carbohydrate diet on lipoprotein subfractions, and on inflammation in high-risk subjects. Both diets had similar effects on LDL and HDL subfractions. Read More
Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet
Mediterranean and low-carbohydrate diets may be effective alternatives to low-fat diets. The more favorable effects on lipids (with the low-carbohydrate diet) and on glycemic control (with the Mediterranean diet) suggest that personal preferences and metabolic considerations might inform individualized tailoring of dietary interventions. Read More