Mental aspects of HRQOL (health related quality of life) improved more in participants following an LCKD (low calorie ketogenic diet) than an LFD (low fat diet), possibly resulting from the LCKD’s composition, lack of explicit energy restriction, higher levels of satiety or metabolic effects. The factors analyzed were: Physical Functioning, Role-Physical, General Health, Vitality, Social Functioning. The Physical Component Summary score improved similarly in both diet groups. Bodily Pain improved in the LFD group only, whereas the Role-Emotional and Mental Health subscales and the Mental Component Summary (MCS) score improved in the LCKD group only.
Category: Ketogenic Diet
A Low-carbohydrate, Ketogenic Diet to Treat Type 2 Diabetes
In a study of overweight individuals with type 2 diabetes, the LCKD (low carbohydrate ketogenic diet) improved glycemic control in patients with type 2 diabetes such that diabetes medications were discontinued or reduced in most participants. Other results include: mean body weight decreased by 6.6% and fasting serum triglyceride decreased 42%.
A Low-Carbohydrate, Ketogenic Diet for Type 2 Diabetes Mellitus
The LCKD reduced glycemia, body weight and serum triglycerides in type 2 diabetic patients but close medical supervision was required to adjust diabetic and blood pressure medications.
A Low-Carbohydrate, Ketogenic Diet versus a Low-Fat Diet To Treat Obesity and Hyperlipidemia: A Randomized, Controlled Trial
Compared with a low-fat diet, a low-carbohydrate diet program had better participant retention and greater weight loss. During active weight loss, serum triglyceride levels decreased more and high-density lipoprotein cholesterol level increased more with the low-carbohydrate diet than with the low-fat diet.
A Pilot Trial of a Low-Carbohydrate, Ketogenic Diet in Patients with Type 2 Diabetes
The study focused on overweight individuals with BMI >25 and being treated with OHA (oral hypoglycemic agents) or insulin that were placed on a LCKD (low carbohydrate ketogenic diet) for 16 weeks. Anthropometric changes include: Body weight = -10%, BMI = -10%, Waist circumference = -7%, Body fat % = -3%, Systolic BP = -9%, Diastolic BP = -15%, Heart Rate = -12%, HDL = no change.
A Pilot Study of a Low-Carbohydrate, Ketogenic Diet for Obesity-Related Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age, and is frequently associated with central obesity, insulin resistance, and dyslipidemia. Because recent evidence demonstrates that a low carbohydrate ketogenic diet (LCKD) leads to weight loss and improvements in insulin sensitivity, we conducted this uncontrolled trial of the diet for PCOS.
A Review of Low-carbohydrate Ketogenic Diets
In response to the emerging epidemic of obesity in the United States, a renewal of interest in alternative diets has occurred, especially in diets that limit carbohydrate intake. Recent research has demonstrated that low-carbohydrate ketogenic diets can lead to weight loss and favorable changes in serum triglycerides and high-density lipoprotein cholesterol. This review summarizes the physiology and recent clinical studies regarding this type of diet.
A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal-weight Men
The results suggest that a short-term ketogenic diet does not have a deleterious effect on CVD risk profile and may improve the lipid disorders characteristic of atherogenic dyslipidemia.
Comparison of Seizure Reduction and Serum Fatty Acid Levels After Receiving the Ketogenic and Modified Atkins Diet
Authors compared retrospectively the KD and modified Atkins diet in 27 children and also assessed serum long chain fatty acid profiles. We observed a preventive effect of both diets on the occurrence of status epilepticus. After 1 and 3 months of either diet, responders experienced a significant decrease in serum arachidonic acid concentration compared to non-responders. The KD and modified Atkins diet led to seizure reduction in this small pilot series, with slightly better results after 3 months with the KD, but not after 6 months.
The Human Metabolic Response to Chronic Ketosis Without Caloric Restriction: Physical and Biochemical Adaptation
These findings indicate that the ketotic state induced by the EKD was well tolerated in lean subjects; nitrogen balance was regained after brief adaptation, serum lipids were not pathologically elevated, and blood glucose oxidation at rest was measurably reduced while the subjects remained euglycemic.