The effects of a low-carbohydrate, ketogenic diet (LCKD) on sleepiness and other narcolepsy symptoms were studied. Nine patients with narcolepsy were asked to adhere to the Atkins’ diet plan, and their symptoms were assessed using the Narcolepsy Symptom Status Questionnaire (NSSQ). The NSSQ-Total score decreased by 18% from 161.9 to 133.5 (p = 0.0019) over 8 weeks. Patients with narcolepsy experienced modest improvements in daytime sleepiness on an LCKD.
Category: Ketogenic Diet
Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes
This study shows the beneficial effects of a ketogenic diet over the conventional LCD in obese diabetic subjects. The ketogenic diet appears to improve glycemic control. Therefore, diabetic patients on a ketogenic diet should be under strict medical supervision because the LCKD can significantly lower blood glucose levels.
Modified Atkins Diet Therapy For a Case With Glucose Transporter Type 1 Deficiency Syndrome
The modified Atkins diet should be considered for patients with GLUT-1 DS as an alternative to the traditional ketogenic diet.
When Do Seizures Usually Improve With The Ketogenic Diet?
The KD works quickly when effective, typically within the first 1–2 weeks. Starting the KD after a fasting periodmay lead to a more rapid, but equivalent long-term seizure reduction, confirming prior reports. If the KD has not led to seizure reduction after 2 months, it can probably be discontinued.
Ketogenic Diets: Evidence For Short- and Long-term Efficacy
This review discusses the animal and human evidence for both short- and long-term benefits of dietary therapies.
A Pilot Study of The Modified Atkins Diet For Sturge–Weber Syndrome
The modified Atkins diet (MAD) is a dietary treatment for epilepsy which does not restrict fluids or calories. This theoretically makes the MAD safer than the ketogenic diet for children with Sturge–Weber syndrome (SWS). Five children aged 4–18 years with SWS and at least monthly intractable seizures were started prospectively on the MAD for 6 months. All children had urinary ketosis and seizure improvement, including 3 with >50% seizure reduction.
Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials
Individuals assigned to a VLCKD achieve a greater weight loss than those assigned to a LFD in the long term; hence, a VLCKD may be an alternative tool against obesity.
Urinary Ketones Reflect Serum Ketone Concentration But Do Not Relate to Weight Loss in Overweight Premenopausal Women Following a Low-carbohydrate/High-protein Diet
Thirteen overweight premenopausal women aged 32 to 45 years consumed <20 g carbohydrate/day with liberal intakes of protein and fat for 2 weeks; thereafter, carbohydrate intake increased 5 g/week for 10 weeks. Serum-hydroxybutyrate was correlated with presence of urinary ketones, but no relationship was found between weekly weight change and serum ketone production. Urinary ketones are detected in premenopausal women complying with a low-carbohydrate/high-protein diet and are associated with serum ketone concentration.
Short-Term Effects of Severe Dietary Carbohydrate-Restriction Advice in Type 2 Diabetes–a Randomized Controlled Trial
Weight loss and high-density lipoprotein (HDL) ratio improved was greater in the low-carbohydrate (LC) group over low fat group. Carbohydrate restriction was an effective method of achieving short-term weight loss compared with standard advice.
Ketogenic Diet Modifies The Risk Factors of Heart Disease in Obese Patients
The level of total cholesterol decreased from week 1 to week 12. HDL cholesterol increased significantly, whereas LDL cholesterol decreased significantly. The purpose of this study was to investigate the long-term effect of a ketogenic diet on the activation and modification of heart disease risk factors in obese patients.